| Orlando, FL → St. Louis, MO | 1275 | $247 | Southwest |
| New York City, NY (Metropolitan Area) → St. Louis, MO | 1110 | $248 | Southwest |
| Phoenix, AZ → St. Louis, MO | 966 | $266 | Southwest |
| Miami, FL (Metropolitan Area) → St. Louis, MO | 946 | $305 | Southwest |
| Las Vegas, NV → St. Louis, MO | 896 | $272 | Southwest |
| Dallas/Fort Worth, TX → St. Louis, MO | 875 | $265 | Southwest |
| Los Angeles, CA (Metropolitan Area) → St. Louis, MO | 871 | $305 | Southwest |
| St. Louis, MO → Washington, DC (Metropolitan Area) | 869 | $268 | Southwest |
| Denver, CO → St. Louis, MO | 819 | $228 | Southwest |
| Atlanta, GA (Metropolitan Area) → St. Louis, MO | 645 | $248 | Delta |
| Houston, TX → St. Louis, MO | 604 | $291 | Southwest |
| St. Louis, MO → Tampa, FL (Metropolitan Area) | 546 | $267 | Southwest |
| Chicago, IL → St. Louis, MO | 539 | $266 | Southwest |
| Fort Myers, FL → St. Louis, MO | 508 | $316 | Southwest |
| Boston, MA (Metropolitan Area) → St. Louis, MO | 394 | $326 | Southwest |
| San Francisco, CA (Metropolitan Area) → St. Louis, MO | 389 | $376 | Southwest |
| Minneapolis/St. Paul, MN → St. Louis, MO | 382 | $293 | Delta |
| Seattle, WA → St. Louis, MO | 353 | $252 | Alaska |
| Austin, TX → St. Louis, MO | 346 | $229 | Southwest |
| San Diego, CA → St. Louis, MO | 343 | $305 | Southwest |
| Charlotte, NC → St. Louis, MO | 305 | $255 | American |
| Philadelphia, PA → St. Louis, MO | 297 | $315 | American |
| Salt Lake City, UT → St. Louis, MO | 296 | $364 | Delta |
| Detroit, MI → St. Louis, MO | 286 | $307 | Delta |
| New Orleans, LA → St. Louis, MO | 255 | $285 | Southwest |
| San Antonio, TX → St. Louis, MO | 231 | $288 | Southwest |
| Raleigh/Durham, NC → St. Louis, MO | 224 | $269 | Southwest |