| New York City, NY (Metropolitan Area) → Orlando, FL | 12092 | $190 | JetBlue |
| Orlando, FL → Washington, DC (Metropolitan Area) | 5456 | $199 | Southwest |
| Chicago, IL → Orlando, FL | 5100 | $214 | United |
| Boston, MA (Metropolitan Area) → Orlando, FL | 4936 | $208 | JetBlue |
| Orlando, FL → Philadelphia, PA | 3634 | $208 | American |
| Detroit, MI → Orlando, FL | 3290 | $231 | Delta |
| Dallas/Fort Worth, TX → Orlando, FL | 3181 | $240 | American |
| Los Angeles, CA (Metropolitan Area) → Orlando, FL | 2928 | $324 | Delta |
| Minneapolis/St. Paul, MN → Orlando, FL | 2907 | $253 | Delta |
| Denver, CO → Orlando, FL | 2601 | $257 | United |
| Houston, TX → Orlando, FL | 2422 | $221 | United |
| Atlanta, GA (Metropolitan Area) → Orlando, FL | 2288 | $215 | Delta |
| Cleveland, OH (Metropolitan Area) → Orlando, FL | 1953 | $178 | Frontier |
| Nashville, TN → Orlando, FL | 1608 | $229 | Southwest |
| Las Vegas, NV → Orlando, FL | 1588 | $270 | Southwest |
| Orlando, FL → Raleigh/Durham, NC | 1538 | $177 | Delta |
| Indianapolis, IN → Orlando, FL | 1518 | $219 | Southwest |
| Orlando, FL → Pittsburgh, PA | 1483 | $215 | Southwest |
| Hartford, CT → Orlando, FL | 1469 | $181 | JetBlue |
| Orlando, FL → Phoenix, AZ | 1439 | $327 | American |
| Cincinnati, OH → Orlando, FL | 1405 | $189 | Frontier |
| Orlando, FL → San Francisco, CA (Metropolitan Area) | 1324 | $361 | United |
| Charlotte, NC → Orlando, FL | 1322 | $223 | American |
| Columbus, OH → Orlando, FL | 1294 | $227 | Southwest |
| Orlando, FL → St. Louis, MO | 1275 | $247 | Southwest |
| Buffalo, NY → Orlando, FL | 1219 | $199 | Southwest |
| Austin, TX → Orlando, FL | 1198 | $234 | Southwest |
| Orlando, FL → Seattle, WA | 1165 | $328 | Alaska |
| Orlando, FL → Salt Lake City, UT | 1156 | $367 | Delta |
| Milwaukee, WI → Orlando, FL | 1118 | $238 | Southwest |
| New Orleans, LA → Orlando, FL | 1105 | $195 | Southwest |
| Kansas City, MO → Orlando, FL | 1037 | $270 | Southwest |
| Orlando, FL → San Diego, CA | 880 | $288 | Alaska |
| Albany, NY → Orlando, FL | 840 | $220 | Southwest |
| Orlando, FL → Richmond, VA | 761 | $174 | JetBlue |
| Orlando, FL → San Antonio, TX | 710 | $232 | Southwest |
| Memphis, TN → Orlando, FL | 584 | $229 | Southwest |
| Orlando, FL → Syracuse, NY | 583 | $218 | JetBlue |
| Orlando, FL → Portland, OR | 577 | $312 | Alaska |
| Orlando, FL → Sacramento, CA | 556 | $258 | Southwest |
| Norfolk, VA (Metropolitan Area) → Orlando, FL | 541 | $176 | Southwest |
| Louisville, KY → Orlando, FL | 521 | $245 | Southwest |
| Grand Rapids, MI → Orlando, FL | 516 | $245 | Frontier |
| Orlando, FL → Rochester, NY | 491 | $230 | Southwest |
| Omaha, NE → Orlando, FL | 465 | $296 | Southwest |
| Birmingham, AL → Orlando, FL | 429 | $285 | Southwest |
| Miami, FL (Metropolitan Area) → Orlando, FL | 410 | $177 | American |
| Orlando, FL → Portland, ME | 400 | $204 | Breeze |
| New Haven, CT → Orlando, FL | 348 | $117 | XP |
| Atlantic City, NJ → Orlando, FL | 316 | $104 | Spirit |
| Orlando, FL → Trenton, NJ | 313 | $126 | Frontier |
| Oklahoma City, OK → Orlando, FL | 304 | $316 | Southwest |
| Madison, WI → Orlando, FL | 263 | $241 | Breeze |
| Orlando, FL → Tulsa, OK | 253 | $275 | Southwest |
| Boise, ID → Orlando, FL | 233 | $292 | Southwest |
| Huntsville, AL → Orlando, FL | 229 | $230 | Breeze |
| Des Moines, IA → Orlando, FL | 225 | $287 | American |
| Latrobe, PA → Orlando, FL | 218 | $112 | Spirit |
| Knoxville, TN → Orlando, FL | 215 | $226 | Allegiant |
| Albuquerque, NM → Orlando, FL | 214 | $295 | Southwest |
| Harrisburg, PA → Orlando, FL | 212 | $198 | Frontier |