| Las Vegas, NV → Los Angeles, CA (Metropolitan Area) | 6146 | $158 | Southwest |
| Las Vegas, NV → San Francisco, CA (Metropolitan Area) | 5452 | $201 | Southwest |
| Las Vegas, NV → New York City, NY (Metropolitan Area) | 4232 | $369 | United |
| Chicago, IL → Las Vegas, NV | 3389 | $257 | United |
| Dallas/Fort Worth, TX → Las Vegas, NV | 3106 | $256 | American |
| Denver, CO → Las Vegas, NV | 2636 | $194 | Southwest |
| Las Vegas, NV → Seattle, WA | 2355 | $199 | Alaska |
| Houston, TX → Las Vegas, NV | 2310 | $256 | United |
| Las Vegas, NV → Minneapolis/St. Paul, MN | 1922 | $255 | Delta |
| Las Vegas, NV → Miami, FL (Metropolitan Area) | 1911 | $352 | American |
| Atlanta, GA (Metropolitan Area) → Las Vegas, NV | 1907 | $410 | Delta |
| Las Vegas, NV → Phoenix, AZ | 1901 | $191 | Southwest |
| Las Vegas, NV → Washington, DC (Metropolitan Area) | 1888 | $371 | Southwest |
| Las Vegas, NV → San Diego, CA | 1863 | $145 | Southwest |
| Las Vegas, NV → Orlando, FL | 1588 | $270 | Southwest |
| Detroit, MI → Las Vegas, NV | 1558 | $317 | Delta |
| Las Vegas, NV → Sacramento, CA | 1535 | $200 | Southwest |
| Las Vegas, NV → Portland, OR | 1504 | $201 | Alaska |
| Boston, MA (Metropolitan Area) → Las Vegas, NV | 1362 | $340 | JetBlue |
| Austin, TX → Las Vegas, NV | 1338 | $253 | Southwest |
| Las Vegas, NV → Salt Lake City, UT | 1183 | $221 | Delta |
| Las Vegas, NV → Reno, NV | 1071 | $195 | Southwest |
| Las Vegas, NV → Philadelphia, PA | 955 | $391 | American |
| Las Vegas, NV → San Antonio, TX | 924 | $262 | Southwest |
| Las Vegas, NV → St. Louis, MO | 896 | $272 | Southwest |
| Las Vegas, NV → Nashville, TN | 891 | $308 | Southwest |
| Cleveland, OH (Metropolitan Area) → Las Vegas, NV | 872 | $239 | Frontier |
| Las Vegas, NV → Tampa, FL (Metropolitan Area) | 856 | $324 | Southwest |
| Kansas City, MO → Las Vegas, NV | 847 | $269 | Southwest |
| Charlotte, NC → Las Vegas, NV | 775 | $418 | American |
| Indianapolis, IN → Las Vegas, NV | 727 | $287 | Southwest |
| Las Vegas, NV → Raleigh/Durham, NC | 668 | $314 | Delta |
| Cincinnati, OH → Las Vegas, NV | 645 | $257 | Delta |
| Las Vegas, NV → New Orleans, LA | 556 | $248 | Southwest |
| Columbus, OH → Las Vegas, NV | 550 | $322 | Southwest |
| Las Vegas, NV → Pittsburgh, PA | 546 | $323 | Southwest |
| Boise, ID → Las Vegas, NV | 525 | $202 | Southwest |
| Albuquerque, NM → Las Vegas, NV | 501 | $232 | Southwest |
| Las Vegas, NV → Milwaukee, WI | 486 | $325 | Southwest |
| Las Vegas, NV → Omaha, NE | 476 | $277 | Southwest |
| Las Vegas, NV → Spokane, WA | 469 | $225 | Southwest |
| El Paso, TX → Las Vegas, NV | 460 | $199 | Southwest |
| Las Vegas, NV → Oklahoma City, OK | 410 | $269 | Southwest |
| Everett, WA → Las Vegas, NV | 387 | $179 | Alaska |
| Fresno, CA → Las Vegas, NV | 387 | $153 | Southwest |
| Las Vegas, NV → Memphis, TN | 345 | $267 | Southwest |
| Des Moines, IA → Las Vegas, NV | 340 | $219 | Allegiant |
| Grand Rapids, MI → Las Vegas, NV | 332 | $229 | Allegiant |
| Las Vegas, NV → Tucson, AZ | 310 | $226 | Southwest |
| Jacksonville, FL → Las Vegas, NV | 301 | $367 | American |
| Hartford, CT → Las Vegas, NV | 293 | $269 | Breeze |
| Las Vegas, NV → Mission/McAllen/Edinburg, TX | 282 | $155 | Allegiant |
| Las Vegas, NV → Louisville, KY | 276 | $301 | Southwest |
| Las Vegas, NV → Tulsa, OK | 272 | $253 | Southwest |
| Fort Myers, FL → Las Vegas, NV | 260 | $372 | Breeze |
| Colorado Springs, CO → Las Vegas, NV | 259 | $226 | Southwest |
| Buffalo, NY → Las Vegas, NV | 255 | $298 | Southwest |
| Las Vegas, NV → Richmond, VA | 255 | $321 | Breeze |
| Birmingham, AL → Las Vegas, NV | 232 | $360 | Southwest |
| Las Vegas, NV → Norfolk, VA (Metropolitan Area) | 225 | $336 | American |
| Eugene, OR → Las Vegas, NV | 220 | $190 | Southwest |
| Knoxville, TN → Las Vegas, NV | 213 | $289 | Allegiant |
| Las Vegas, NV → Wichita, KS | 210 | $213 | Southwest |