| Denver, CO → Los Angeles, CA (Metropolitan Area) | 4571 | $216 | United |
| Denver, CO → Phoenix, AZ | 3677 | $194 | Southwest |
| Denver, CO → New York City, NY (Metropolitan Area) | 3556 | $270 | United |
| Dallas/Fort Worth, TX → Denver, CO | 3008 | $198 | Southwest |
| Chicago, IL → Denver, CO | 2731 | $210 | United |
| Denver, CO → San Francisco, CA (Metropolitan Area) | 2675 | $261 | United |
| Denver, CO → Las Vegas, NV | 2636 | $194 | Southwest |
| Denver, CO → Washington, DC (Metropolitan Area) | 2605 | $282 | United |
| Denver, CO → Orlando, FL | 2601 | $257 | United |
| Denver, CO → Miami, FL (Metropolitan Area) | 2412 | $279 | United |
| Denver, CO → Houston, TX | 2403 | $228 | United |
| Denver, CO → San Diego, CA | 2078 | $169 | Southwest |
| Atlanta, GA (Metropolitan Area) → Denver, CO | 1842 | $249 | Delta |
| Denver, CO → Seattle, WA | 1698 | $193 | Alaska |
| Denver, CO → Minneapolis/St. Paul, MN | 1647 | $194 | Delta |
| Boston, MA (Metropolitan Area) → Denver, CO | 1618 | $248 | United |
| Austin, TX → Denver, CO | 1611 | $200 | Southwest |
| Denver, CO → Tampa, FL (Metropolitan Area) | 1561 | $243 | United |
| Denver, CO → Salt Lake City, UT | 1554 | $193 | Delta |
| Denver, CO → Nashville, TN | 1004 | $238 | Southwest |
| Denver, CO → Philadelphia, PA | 994 | $287 | American |
| Denver, CO → Detroit, MI | 954 | $239 | Delta |
| Denver, CO → Portland, OR | 918 | $200 | United |
| Charlotte, NC → Denver, CO | 874 | $226 | American |
| Denver, CO → New Orleans, LA | 832 | $236 | United |
| Denver, CO → San Antonio, TX | 821 | $210 | Southwest |
| Denver, CO → St. Louis, MO | 819 | $228 | Southwest |
| Denver, CO → Kansas City, MO | 815 | $213 | Southwest |
| Denver, CO → Raleigh/Durham, NC | 682 | $257 | United |
| Denver, CO → Indianapolis, IN | 669 | $242 | Southwest |
| Denver, CO → Sacramento, CA | 665 | $236 | United |
| Denver, CO → Fort Myers, FL | 616 | $337 | United |
| Denver, CO → Tucson, AZ | 555 | $217 | United |
| Cleveland, OH (Metropolitan Area) → Denver, CO | 504 | $243 | United |
| Cincinnati, OH → Denver, CO | 494 | $222 | United |
| Denver, CO → Oklahoma City, OK | 453 | $204 | Southwest |
| Denver, CO → Omaha, NE | 421 | $195 | United |
| Denver, CO → Palm Springs, CA | 414 | $309 | United |
| Columbus, OH → Denver, CO | 408 | $277 | United |
| Denver, CO → Jacksonville, FL | 389 | $345 | United |
| Boise, ID → Denver, CO | 387 | $224 | United |
| Albuquerque, NM → Denver, CO | 380 | $220 | Southwest |
| Denver, CO → Pittsburgh, PA | 374 | $323 | United |
| Denver, CO → Milwaukee, WI | 355 | $264 | Southwest |
| Denver, CO → El Paso, TX | 350 | $172 | Southwest |
| Denver, CO → West Palm Beach/Palm Beach, FL | 347 | $327 | United |
| Denver, CO → Pensacola, FL | 334 | $227 | Frontier |
| Denver, CO → Memphis, TN | 307 | $229 | United |
| Denver, CO → Reno, NV | 305 | $294 | United |
| Bozeman, MT → Denver, CO | 294 | $209 | United |
| Denver, CO → Tulsa, OK | 284 | $226 | Southwest |
| Denver, CO → Madison, WI | 273 | $235 | United |
| Denver, CO → Spokane, WA | 263 | $250 | United |
| Denver, CO → Hartford, CT | 260 | $343 | United |
| Charleston, SC → Denver, CO | 252 | $303 | United |
| Denver, CO → Grand Rapids, MI | 242 | $288 | United |
| Denver, CO → Des Moines, IA | 242 | $229 | United |
| Denver, CO → Richmond, VA | 235 | $295 | United |
| Denver, CO → Knoxville, TN | 220 | $264 | United |
| Denver, CO → Sarasota/Bradenton, FL | 213 | $342 | Southwest |
| Cedar Rapids/Iowa City, IA → Denver, CO | 210 | $198 | United |
| Birmingham, AL → Denver, CO | 207 | $319 | Southwest |